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Article

Screening for effectors that modify multidrug resistance in yeast.

International journal of antimicrobial agents - 1 Sept 2003

Kozovská Zuzana, Subik Julius

Abstract excerpt

The yeast transcription factors Pdr1p and Pdr3p regulate the expression of several genes that encode energy-dependent efflux pumps involved in multidrug resistance. They recognize specific pleiotropic drug resistance elements in the promoters of the target gene such as PDR5 coding for a major multidrug transporter. Gain-of-function mutations in Pdr1p/Pdr3p result in over-expression of transporter genes and...

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Identifiers

PMID: 13678836
DOI: 10.1016/s0924-8579(03)00216-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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