Article
Tumor necrosis factor genomic polymorphism in Spanish IGA deficiency patients.
Tissue antigens - 1 Apr 2000
De la Concha E G, Fernandez-Arquero M, Vigil P, Lazaro F, Ferreira A, Garcia-Rodriguez M C, Fontan G
Abstract excerpt
Selective IgA deficiency (IgAD) is the most common form of primary immunodeficiency. Its association with genes within the major histocompatibility complex (MHC) has been repeatedly reported. Recently the susceptibility gene has been located in the class III region, around the tumor necrosis factor (TNF) cluster. In this study we have examined IgAD association with TNF-alpha gene promoter polymorphisms and TNFa...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
