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Interleukin-6 gene variation in Spanish patients with immunoglobulin-A deficiency.

Human immunology - 1 Jan 2000

López-Mejías Raquel, Martínez Alfonso, Del Pozo Nadia, Fernández-Arquero Miguel, Ferreira Antonio, Urcelay Elena, Fontán Gumersindo, de la Concha Emilio G, Núñez Concepción

Abstract excerpt

Selective immunoglobulin-A deficiency (IgAD) is the most common immunodeficiency in Caucasian populations. Genetic factors are important in its etiology; however human leukocyte antigen (HLA) genes, which explain 40% of the genetic risk for IgAD, are the only susceptibility factors commonly agreed upon at this time. Because interleukin-6 (IL-6) plays an important role in B-lymphocyte differentiation from plasma...

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Identifiers

PMID: 18486766
DOI: 10.1016/j.humimm.2008.02.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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