Article
Human leukocyte antigens (HLA) associated with selective IgA deficiency in Iran and Sweden.
Iranian journal of allergy, asthma, and immunology - 1 Dec 2008
Mohammadi Javad, Pourpak Zahra, Jarefors Sara, Saghafi Shiva, Zendehdel Kazem, Pourfathollah Ali Akbar, Amirzargar Ali Akbar, Aghamohammadi Asghar, Moin Mostafa, Hammarstrom Lennart
Abstract excerpt
Selective IgA deficiency (IgAD) (serum IgA concentration of <0.07 g/l) is the most common primary immunodeficiency in Caucasians, with an estimated prevalence of 1/600. There are strong indications for involvement of genetic factors in development of the disease and the frequency of several extended major histocompatibility complex haplotypes (including HLA-A1, B8, DR3, DQ2) have previously been shown to be...
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