Article
Role of polymorphisms in the TNFRSF13B (TACI) gene in Spanish patients with immunoglobulin A deficiency.
Tissue antigens - 1 Jul 2009
López-Mejías R, del Pozo N, Fernández-Arquero M, Ferreira A, García-Rodríguez M C, de la Concha E G, Fontán G, Urcelay E, Martínez A, Núñez C
Abstract excerpt
Mutations in the TNFRSF13B (TACI) gene have been associated with common variable immunodeficiency, and a role in immunoglobulin A deficiency (IgAD) has also been suggested. We aimed at studying the role of several polymorphisms along this gene in IgAD susceptibility. Three TNFRSF13B mutations (C104R, A181E and R202H) and eight additional single nucleotide polymorphisms in the gene were genotyped in 338 Spanish...
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