Article
Necessity of biotherapeutic treatments inducing TH1 cell functions in colorectal cancer.
Cancer biotherapy & radiopharmaceuticals - 1 Dec 1996
Contasta I, Pellegrini P, Berghella A M, Del Beato T, Canossi A, Di Rocco M, Adorno D, Casciani C U
Abstract excerpt
Our previous data on colorectal cancer suggest that there are faults at the level of mechanisms of the proliferative responses of patients peripheral blood mononuclear cells (PBMC) to the interleukin (IL)-2 and IL-2 PBMC production, which increase with the stage advancement. The damages in the proliferative response seem to be eliminated by the costimulator effects of the signals produced by the anti-CD3...
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