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Article

Chemotherapy ± cetuximab modulates peripheral immune responses in metastatic colorectal cancer.

Oncology - 1 Jan 2013

Xynos Ioannis D, Karadima Maria L, Voutsas Ioannis F, Amptoulach Sousana, Skopelitis Elias, Kosmas Christos, Gritzapis Angelos D, Tsavaris Nikolas

Abstract excerpt

OBJECTIVE: To identify changes in peripheral immune responses in patients with metastatic colorectal cancer (mCRC) treated with irinotecan/5-fluorouracil/leucovorin (IFL) alone or in combination with cetuximab (C-IFL). METHODS: Peripheral blood mononuclear cells (PBMCs) collected from healthy donors (n = 20) and patients with mCRC receiving treatment with either IFL (n = 30) or C-IFL (n = 30) were tested for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23445638
DOI: 10.1159/000343282

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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