Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human T-cell receptor BV6 gene polymorphism in relation to expression level and CD4/CD8 skewness.

Scandinavian journal of immunology - 1 Jun 2000

Obata F, Shiiba R, Iizuka M, Kashiwagi N, Kurosu F, Shimada N, Nishijima M, Tozawa H

Abstract excerpt

Using 50 samples of umbilical cord blood lymphocytes from Japanese donors, we analysed two human T-cell receptor beta variable (TCRBV) genes, BV6S4 and BV6S5, for their polymorphism, usage frequencies and CD4/CD8 skewness. They showed contrasting CD4/CD8 skewness, BV6S4 to CD8+ T cells and BV6S5 to CD4+ T cells. Genotyping of the BV6S4 alleles (A1, A2 and A3) revealed two of the six possible BV6S4 genotypes,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD4 Antigens
Share to CD4-CD8 Ratio
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CD8 Antigens

Share to CD8-Positive T-Lymphocytes

Share to Fetal Blood

Share to Genes, T-Cell Receptor beta

Share to Receptors, Antigen, T-Cell, alpha-beta

Source

Identifiers

PMID: 10849363
DOI: 10.1046/j.1365-3083.2000.00717.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Human T-cell receptor BV6 gene polymorphism in relation to expression level and CD4/CD8 skewness.PMID 10849363Read ↗

The human T-cell receptor variable gene segment TCRBV6S1 has two null alleles.Semantic proximity Read ↗

TCRBV12 genes are polymorphic but the protein products encoded by each gene are conserved.Semantic proximity Read ↗

PCR-based genotyping and haplotype analysis of human TCRBV gene segment polymorphisms.Semantic proximity Read ↗

A novel polymorphism in the pseudogene TCRBV5S5 combines with TCRBV6S1 to define three haplotypes.Semantic proximity Read ↗

Allelic variants of human TCR BV17S1 defined by restriction fragment length polymorphism, single strand conformation polymorphism, and amplification refractory mutation system analyses.Semantic proximity Read ↗

Level of human TCRBV3S1 (V beta 3) expression correlates with allelic polymorphism in the spacer region of the recombination signal sequence.Semantic proximity Read ↗

Influence of coding region polymorphism on the peripheral expression of a human TCR V beta gene.Semantic proximity Read ↗

High frequency of the TCRBV20S1 null allele in the Sardinian population.Semantic proximity Read ↗

A bias in the alphabeta T cell receptor variable region gene usage in Takayasu's arteritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.