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Article

S gene (Corneodesmosin) diversity and its relationship to psoriasis; high content of cSNP in the HLA-linked S gene.

The Journal of investigative dermatology - 1 Jun 2000

Enerbäck C, Enlund F, Inerot A, Samuelsson L, Wahlström J, Swanbeck G, Martinsson T

Abstract excerpt

Psoriasis is a heterogeneous disease in which several reports suggest the presence of a susceptibility gene in or in the proximity of the human leukocyte antigen complex in chromosome 6p. There is an association between HLA-Cw6 and young onset of the disease. The S gene (corneodesmosin), located...

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Identifiers

PMID: 10844560
DOI: 10.1046/j.1523-1747.2000.00002.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10844560-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

S gene (Corneodesmosin) diversity and its relationship to psoriasis; high content of cSNP in the HLA-linked S gene.PMID 10844560Read ↗

Novel genetic association between the corneodesmosin (MHC S) gene and susceptibility to psoriasis.Semantic proximity Read ↗

Identification of six novel polymorphisms in the human corneodesmosin gene.Semantic proximity Read ↗

Corneodesmosin gene polymorphism demonstrates strong linkage disequilibrium with HLA and association with psoriasis vulgaris.Semantic proximity Read ↗

Mapping of the major psoriasis-susceptibility locus (PSORS1) in a 70-Kb interval around the corneodesmosin gene (CDSN).Semantic proximity Read ↗

Stronger association with HLA-Cw6 than with corneodesmosin (S-gene) polymorphisms in Swedish psoriasis patients.Semantic proximity Read ↗

Comparative association analysis reveals that corneodesmosin is more closely associated with psoriasis than HLA-Cw*0602-B*5701 in German families.Semantic proximity Read ↗

Psoriasis is associated with a SNP haplotype of the corneodesmosin gene (CDSN).Semantic proximity Read ↗

Corneodesmosin (CDSN) gene association with psoriasis vulgaris in Caucasian but not in Japanese populations.Semantic proximity Read ↗

Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene.Semantic proximity Read ↗

Corneodesmosin gene: no evidence for PSORS 1 gene in North-eastern Thai psoriasis patients.Semantic proximity Read ↗

Localization of PSORS1 to a haplotype block harboring HLA-C and distinct from corneodesmosin and HCR.Semantic proximity Read ↗

Localization of psoriasis-susceptibility locus PSORS1 to a 60-kb interval telomeric to HLA-C.Semantic proximity Read ↗

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