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Article

Phosphorylation at tyrosine-524 influences nuclear accumulation of HSP72 with heat stress.

American journal of physiology. Heart and circulatory physiology - 1 Jun 2000

Knowlton A A, Grenier M, Kirchhoff S R, Salfity M

Abstract excerpt

Nuclear accumulation of heat shock protein (HSP) 72 occurs after cardiac ischemia. This nuclear accumulation of HSP72 with stress occurs in other tissues and species. We postulated that nuclear accumulation of HSP72 was important for the protective effect of HSP72 and that phosphorylation of a single tyrosine (Y(524)) regulated nuclear accumulation of HSP72. Western blots of immunoprecipitated HSP72 from Cos-1...

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Identifiers

PMID: 10843914
DOI: 10.1152/ajpheart.2000.278.6.H2143

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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