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Article

Translational thermotolerance provided by small heat shock proteins is limited to cap-dependent initiation and inhibited by 2-aminopurine.

The Journal of biological chemistry - 12 Dec 2003

Doerwald Linda, Onnekink Carla, van Genesen Siebe T, de Jong Wilfried W, Lubsen Nicolette H

Abstract excerpt

Heat shock results in inhibition of general protein synthesis. In thermotolerant cells, protein synthesis is still rapidly inhibited by heat stress, but protein synthesis recovers faster than in naive heat-shocked cells, a phenomenon known as translational thermotolerance. Here we investigate the...

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Identifiers

PMID: 14523008
DOI: 10.1074/jbc.M302914200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14523008-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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