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Article

Early auditory sensory processing deficits in mouse mutants with reduced NMDA receptor function.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jun 2008

Bickel Stephan, Lipp Hans-Peter, Umbricht Daniel

Abstract excerpt

Cognitive deficits in schizophrenia include impairments at automatic, preattentive stages of sensory information processing. These deficits are evident in the prepulse inhibition- (PPI) and habituation of the auditory startle response paradigm, the paired tone paradigm in the EEG, and the peak recovery function of auditory evoked potentials (AEP). Administration of NMDA receptor antagonists reliably disrupts PPI...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Evoked Potentials, Auditory

Share to Habituation, Psychophysiologic

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Share to Receptors, N-Methyl-D-Aspartate

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Source

Identifiers

PMID: 17712349
DOI: 10.1038/sj.npp.1301536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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