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Article

A novel rat strain with enhanced sensitivity to the effects of dopamine agonists on startle gating.

Pharmacology, biochemistry, and behavior - 1 Jan 2008

Swerdlow Neal R, Breier Michelle, Mora Adrienne B, Ko David, Shoemaker Jody M

Abstract excerpt

BACKGROUND: Compared to outbred Sprague Dawley (SD) rats, inbred Brown Norway (BN) rats exhibit less prepulse inhibition of startle (PPI) at long prepulse intervals, and more PPI at short intervals. Sensitivity to dopaminergic drug effects on PPI differs substantially across strains, and is heritable within SD and other outbred strains. To further understand the heritability of PPI and its sensitivity to dopamine...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17936348
DOI: 10.1016/j.pbb.2007.08.013
PMCID: PMC2585785

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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