Article
Chaperone-like activity of synucleins.
FEBS letters - 26 May 2000
Souza J M, Giasson B I, Lee V M, Ischiropoulos H
Abstract excerpt
Synucleins are a family of small proteins that are predominantly expressed in neurons. The functions of the synucleins are not entirely understood, but they have been implicated in the pathogenesis of several neurodegenerative diseases. Our data show that alpha-, beta- or gamma-synuclein suppresses the aggregation of thermally denatured alcohol dehydrogenase and chemically denatured insulin. The A53T but not the...
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