Article
Polymorphism in oestrogen response element associated with variation in plasma angiotensinogen concentrations in healthy pregnant women.
Journal of hypertension - 1 May 2000
Morgan L, Crawshaw S, Baker P N, Broughton Pipkin F, Kalsheker N
Abstract excerpt
OBJECTIVE: To investigate the hypothesis that the genotype at nucleotide A(-20)C in the 5' flanking region of the angiotensinogen gene, which lies within a sequence with high homology to an oestrogen response element, affects plasma angiotensinogen levels in pregnancy. DESIGN: Prospective observational study METHODS: Seventy-two healthy pregnant women were recruited in the second half of pregnancy from hospital...
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