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Article

Angiotensinogen T235 expression is elevated in decidual spiral arteries.

The Journal of clinical investigation - 15 Sept 1997

Morgan T, Craven C, Nelson L, Lalouel J M, Ward K

Abstract excerpt

Preeclampsia is associated with a common molecular variant of angiotensinogen (Met235Thr). This variant is in tight linkage disequilibrium with a mutation in the angiotensinogen promoter, G(-6)A, which leads to elevated expression in vitro. Since angiotensin II levels could play a role in atherotic changes of the uterine spiral arteries associated with preeclampsia, we investigated angiotensinogen expression in...

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Identifiers

PMID: 9294106
DOI: 10.1172/JCI119661
PMCID: PMC508319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Angiotensinogen T235 expression is elevated in decidual spiral arteries.PMID 9294106Read ↗

Angiotensinogen Thr235 variant is associated with abnormal physiologic change of the uterine spiral arteries in first-trimester decidua.Semantic proximity Read ↗

Human Spiral Artery Renin-Angiotensin SystemSemantic proximity Read ↗

Placental abruption is more frequent in women with the angiotensinogen Thr235 mutation.Semantic proximity Read ↗

A molecular variant of angiotensinogen is associated with idiopathic intrauterine growth restriction.Semantic proximity Read ↗

The combination of maternal KIR-B and fetal HLA-C2 is associated with decidua basalis acute atherosis in pregnancies with preeclampsia.Semantic proximity Read ↗

Polymorphism in oestrogen response element associated with variation in plasma angiotensinogen concentrations in healthy pregnant women.Semantic proximity Read ↗

Definitive Molecular Evidence of Renin-Angiotensin System in Human Uterine Decidual CellsSemantic proximity Read ↗

Preeclampsia risk and angiotensinogen polymorphisms M235T and AGT -217 in African American and Caucasian women.Semantic proximity Read ↗

Angiotensinogen M235T polymorphism is associated with plasma angiotensinogen and cardiovascular disease.Semantic proximity Read ↗

Allele-specific expression of angiotensinogen in human subcutaneous adipose tissue.Semantic proximity Read ↗

Is angiotensinogen gene polymorphism associated with hypertension in pregnancy?Semantic proximity Read ↗

Maternal and fetal angiotensinogen gene allele sharing in pre-eclampsia.Semantic proximity Read ↗

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