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Article

Functional variants of the angiotensinogen gene determine antihypertensive responses to angiotensin-converting enzyme inhibitors in subjects of African origin.

Journal of hypertension - 1 Jun 2006

Woodiwiss Angela J, Nkeh Benedicta, Samani Nilesh J, Badenhorst Danelle, Maseko Muzi, Tiago Armindo D, Candy Geoffrey P, Libhaber Elena, Sareli Pinhas, Brooksbank Richard, Norton Gavin R

Abstract excerpt

OBJECTIVE: To determine whether the response to angiotensin-converting enzyme inhibitor (ACEI) monotherapy in subjects of African origin is determined by genetic variants within the angiotensinogen (AGT) gene. METHODS: A total of 194 hypertensive patients of African ancestry were recruited from district clinics in Johannesburg, South Africa. Eighty patients received open-label ACEI (enalapril or lisinopril)...

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Source

Identifiers

PMID: 16685205
DOI: 10.1097/01.hjh.0000226195.59428.57

Genes

DBP
AGT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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