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Article

Prion Strain Diversity.

Cold Spring Harbor perspectives in medicine - 1 Dec 2016

Bartz Jason C

Abstract excerpt

Prion diseases affect a wide range of mammal species and are caused by a misfolded self-propagating isoform (PrPSc) of the normal prion protein (PrPC). Distinct strains of prions exist and are operationally defined by differences in a heritable phenotype under controlled experimental transmission conditions. Prion strains can differ in incubation period, clinical signs of disease, tissue tropism, and host range....

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Identifiers

PMID: 27908925
DOI: 10.1101/cshperspect.a024349
PMCID: PMC5131755

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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