Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy.

doi:10.1128/JVI.68.12.7859-7868.1994

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Article

Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy.

Journal of virology - 1 Dec 1994

Bessen R A, Marsh R F

Abstract excerpt

The molecular basis of strain variation in scrapie diseases is unknown. The only identified component of the agent is the posttranslationally modified host prion protein (PrPSc). The biochemical and physical properties of PrP from two strains of transmissible mink encephalopathy (TME), called hyp...

Topics

Amino Acid Sequence
Animals
Brain
Cricetinae
Genetic Variation
Male
Mesocricetus
Microsomes
Mink
Molecular Sequence Data
Organ Specificity
Prion Diseases
Prions
Protein Processing, Post-Translational

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