Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Short communication. The effects of drinking and smoking on the CYP2D6 metabolic capacity.

Drug metabolism and disposition: the biological fate of chemicals - 1 Jun 2000

Vincent-Viry M, Fournier B, Galteau M M

Abstract excerpt

We studied the influence of drinking and smoking habits on CYP2D6 metabolic capacity measured by the use of debrisoquine as a substance test. We did not find any significant differences in the frequency of subjects with CYP2D6 deficiency (poor metabolizers) among four groups of healthy individuals: nonsmokers/nondrinkers, smokers/drinkers, nondrinkers/smokers, and nonsmokers/drinkers. We demonstrated that, among...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Drinking
Share to Body Weight
Share to Cytochrome P-450 CYP2D6

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phenotype

Share to Polymorphism, Genetic

Share to Smoking

Source

Identifiers

PMID: 10820131

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Short communication. The effects of drinking and smoking on the CYP2D6 metabolic capacity.PMID 10820131Read ↗

Human CYP2D6 gene polymorphism in Slovene cancer patients and healthy controls.Semantic proximity Read ↗

CYP2D6 phenotypes among Malays in Malaysia.Semantic proximity Read ↗

Is debrisoquine hydroxylation modified during acute viral hepatitis?Semantic proximity Read ↗

CYP2D6 ultrarapid metabolizer genotype as a potential modifier of smoking behaviour.Semantic proximity Read ↗

Inhibition of debrisoquine hydroxylation with quinidine in subjects with three or more functional CYP2D6 genes.Semantic proximity Read ↗

The influence of environmental and genetic factors on CYP2D6, CYP1A2 and UDP-glucuronosyltransferases in man using sparteine, caffeine, and paracetamol as probes.Semantic proximity Read ↗

Molecular basis of genetic variation in debrisoquin hydroxylation in Chinese subjects: polymorphism in RFLP and DNA sequence of CYP2D6.Semantic proximity Read ↗

Genetic basis for differences in debrisoquin polymorphism between a Spanish and other white populations.Semantic proximity Read ↗

Reduced CYP2D6 activity is a negative risk factor for methamphetamine dependence.Semantic proximity Read ↗

Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin.Semantic proximity Read ↗

Interethnic differences in drug metabolism: influence of genetic and environmental factors on debrisoquine hydroxylation phenotype.Semantic proximity Read ↗

CYP1A1 and CYP2D6 polymorphism and risk of lung cancer in a North Indian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.