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Article

Evidence for a gene influencing the TG/HDL-C ratio on chromosome 7q32.3-qter: a genome-wide scan in the Framingham study.

Human molecular genetics - 22 May 2000

Shearman A M, Ordovas J M, Cupples L A, Schaefer E J, Harmon M D, Shao Y, Keen J D, DeStefano A L, Joost O, Wilson P W, Housman D E, Myers R H

Abstract excerpt

Some studies show that plasma triglyceride (TG) levels are a significant independent risk factor for cardiovascular disease (CVD). TG levels are inversely correlated with high density lipoprotein cholesterol (HDL-C) levels, and their metabolism may be closely interrelated. Therefore, the TG/HDL-C ratio may be a relevant CVD risk factor. Our analysis of families in the Framingham Heart Study gave a genetic...

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Identifiers

PMID: 10814713
DOI: 10.1093/hmg/9.9.1315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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