Article
Pleiotropic effects of lipid genes on plasma glucose, HbA1c, and HOMA-IR levels.
Diabetes - 1 Sept 2014
Li Naishi, van der Sijde Marijke R, Bakker Stephan J L, Dullaart Robin P F, van der Harst Pim, Gansevoort Ron T, Elbers Clara C, Wijmenga Cisca, Snieder Harold, Hofker Marten H, Fu Jingyuan
Abstract excerpt
Dyslipidemia is strongly associated with raised plasma glucose levels and insulin resistance (IR), and genome-wide association studies have identified 95 loci that explain a substantial proportion of the variance in blood lipids. However, the loci's effects on glucose-related traits are largely unknown. We have studied these lipid loci and tested their association collectively and individually with fasting plasma...
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