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Article

Nucleotide excision repair endonuclease genes in Drosophila melanogaster.

Mutation research - 28 Apr 2000

Sekelsky J J, Hollis K J, Eimerl A I, Burtis K C, Hawley R S

Abstract excerpt

Nucleotide excision repair (NER) is the primary pathway for the removal of ultraviolet light-induced damage and bulky adducts from DNA in eukaryotes. During NER, the helix is unwound around the damaged site, and incisions are made on the 5' and 3' sides, to release an oligonucleotide carrying the lesion. Repair synthesis can then proceed, using the intact strand as a template. The incisions flanking the lesion...

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Source

Identifiers

PMID: 10812334
DOI: 10.1016/s0921-8777(99)00075-0

Genes

ERCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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