Article
SHOC1 and PTD form an XPF-ERCC1-like complex that is required for formation of class I crossovers.
Journal of cell science - 15 Aug 2011
Macaisne Nicolas, Vignard Julien, Mercier Raphaël
Abstract excerpt
Two distinct pathways for meiotic crossover formation coexist in most eukaryotes. The Arabidopsis SHOC1 protein is required for class I crossovers and shows sequence similarity with the XPF endonuclease family. Active XPF endonucleases form a heterodimer with ERCC1 proteins. Here, we show that PTD, an ERCC1-like protein, is required for class-I-interfering crossovers along with SHOC1, MSH4, MSH5, MER3 and MLH3....
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