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Article

Drosophila ERCC1 is required for a subset of MEI-9-dependent meiotic crossovers.

Genetics - 1 Aug 2005

Radford Sarah J, Goley Elizabeth, Baxter Kimberly, McMahan Susan, Sekelsky Jeff

Abstract excerpt

Drosophila MEI-9 is the catalytic subunit of a DNA structure-specific endonuclease required for nucleotide excision repair (NER). The enzymatic activity of this endonuclease during NER requires the presence of a second, noncatalytic subunit called ERCC1. In addition to its role in NER, MEI-9 is required for the generation of most meiotic crossovers. To better understand the role of MEI-9 in crossover formation,...

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Source

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Identifiers

PMID: 15944364
DOI: 10.1534/genetics.104.036178
PMCID: PMC1255914

Genes

ERCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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