Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Drosophila hold'em is required for a subset of meiotic crossovers and interacts with the dna repair endonuclease complex subunits MEI-9 and ERCC1.

Genetics - 1 Jan 2009

Joyce Eric F, Tanneti S Nikhila, McKim Kim S

Abstract excerpt

Three Drosophila proteins, ERCC1, MUS312, and MEI-9, function in a complex proposed to resolve double-Holliday-junction intermediates into crossovers during meiosis. We report here the characterization of hold'em (hdm), whose protein product belongs to a single-strand-DNA-binding superfamily of p...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Crossing Over, Genetic
Share to DNA Breaks, Double-Stranded
Share to Meiosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Methyl Methanesulfonate

Share to Mutagens

Share to Nondisjunction, Genetic

Share to Protein Subunits

Share to Two-Hybrid System Techniques

Source

Open in PubMed Open full text

Identifiers

PMID: 18957705
DOI: 10.1534/genetics.108.093104
PMCID: PMC2621184

Genes

ERCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18957705-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Drosophila hold'em is required for a subset of meiotic crossovers and interacts with the dna repair endonuclease complex subunits MEI-9 and ERCC1.PMID 18957705Read ↗

Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination.Semantic proximity Read ↗

Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvase.Semantic proximity Read ↗

Drosophila ERCC1 is required for a subset of MEI-9-dependent meiotic crossovers.Semantic proximity Read ↗

Single Holliday junctions are intermediates of meiotic recombination.Semantic proximity Read ↗

Temporally and biochemically distinct activities of Exo1 during meiosis: double-strand break resection and resolution of double Holliday junctions.Semantic proximity Read ↗

Heteroduplex DNA in meiotic recombination in Drosophila mei-9 mutants.Semantic proximity Read ↗

<i>mlh3</i> separation of function and endonuclease defective mutants display an unexpected effect on meiotic recombination outcomesSemantic proximity Read ↗

Nucleotide excision repair endonuclease genes in Drosophila melanogaster.Semantic proximity Read ↗

mlh3 mutations in baker's yeast alter meiotic recombination outcomes by increasing noncrossover events genome-wide.Semantic proximity Read ↗

SHOC1 and PTD form an XPF-ERCC1-like complex that is required for formation of class I crossovers.Semantic proximity Read ↗

Drosophila FANCM helicase prevents spontaneous mitotic crossovers generated by the MUS81 and SLX1 nucleases.Semantic proximity Read ↗

Three structure-selective endonucleases are essential in the absence of BLM helicase in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.