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Function and Interactions of ERCC1-XPF in DNA Damage Response

5 Dec 2018

Abstract excerpt

Numerous proteins are involved in the multiple pathways of the DNA damage response network and play a key role to protect the genome from the wide variety of damages that can occur to DNA. An example of this is the structure-specific endonuclease ERCC1-XPF. This heterodimeric complex is in particular involved in nucleotide excision repair (NER), but also in double strand break repair and interstrand cross-link...

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PMID: 30563071
DOI: 10.3390/molecules23123205

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