Article
Molecular analysis of Irish sheep scrapie cases.
The Journal of general virology - 1 Jun 2000
Sweeney T, Kuczius T, McElroy M, Gómez Parada M, Groschup M H, Parada M G
Abstract excerpt
Different strains of transmissible spongiform encephalopathies in humans and rodent models are associated with the accumulation of PrP(Sc) of distinct molecular characteristics. These characteristics include glycosylation profiles, fragment sizes and long-term resistance of PrP(Sc) to proteinase K. The first objective of this study was to determine the applicability of these criteria to characterize and...
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