Article
L-BSE experimentally transmitted to sheep presents as a unique disease phenotype.
Veterinary research - 8 Nov 2016
Simmons Marion M, Chaplin Melanie J, Konold Timm, Casalone Cristina, Beck Katy E, Thorne Leigh, Everitt Sharon, Floyd Tobias, Clifford Derek, Spiropoulos John
Abstract excerpt
Apart from prion protein genotype, the factors determining the host range and susceptiblity for specific transmissible spongiform encephalopathy agents remain unclear. It is known that bovine atypical L-BSE can transmit to a range of species including primates and humanised transgenic mice. It is important, therefore, that there is as broad an understanding as possible of how such isolates might present in food...
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