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Article

The sno gene, which encodes a component of the histone deacetylase complex, acts as a tumor suppressor in mice.

The EMBO journal - 15 May 2000

Shinagawa T, Dong H D, Xu M, Maekawa T, Ishii S

Abstract excerpt

The Ski and Sno oncoproteins are components of a macromolecular complex containing the co-repressor N-CoR/SMRT, mSin3 and histone deacetylase. This complex has been implicated in the transcriptional repression exerted by a number of repressors including nuclear hormone receptors and Mad. Further more, Ski and Sno negatively regulate transforming growth factor-beta (TGF-beta) signaling by recruiting this complex...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10811619
DOI: 10.1093/emboj/19.10.2280
PMCID: PMC384369

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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