Article
The Sno oncogene antagonizes Wingless signaling during wing development in Drosophila.
PloS one - 16 Jul 2010
Quijano Janine C, Stinchfield Michael J, Zerlanko Brad, Gibbens Ying Y, Takaesu Norma T, Hyman-Walsh Cathy, Wotton David, Newfeld Stuart J
Abstract excerpt
The Sno oncogene (Snoo or dSno in Drosophila) is a highly conserved protein and a well-established antagonist of Transforming Growth Factor-beta signaling in overexpression assays. However, analyses of Sno mutants in flies and mice have proven enigmatic in revealing developmental roles for Sno proteins. Thus, to identify developmental roles for dSno we first reconciled conflicting data on the lethality of dSno...
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