Article
Formation and malformation of the vertebrate left-right axis.
Current molecular medicine - 1 Feb 2002
Hackett Brian P
Abstract excerpt
Despite an externally symmetric body plan, the internal viscera of all vertebrates are asymmetric with respect to the left-right body axis. Determination of the handedness of this asymmetry is nonrandom and highly conserved among vertebrates. Errors in patterning along the left-right axis, which occur in about 1 in 10,000 human births, may result in significant morbidity and mortality. During early embryonic...
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