Article
Sorting to synaptic-like microvesicles from early and late endosomes requires overlapping but not identical targeting signals.
Molecular biology of the cell - 1 May 2000
Blagoveshchenskaya A D, Cutler D F
Abstract excerpt
In PC12 neuroendocrine cells, synaptic-like microvesicles (SLMV) are thought to be formed by two pathways. One pathway sorts the proteins to SLMV directly from the plasma membrane (or a specialized domain thereof) in an adaptor protein complex 2-dependent, brefeldin A (BFA)-insensitive manner. Another pathway operates via an endosomal intermediate, involves adaptor protein complex 3, and is BFA sensitive. We have...
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