Article
A selective transport route from Golgi to late endosomes that requires the yeast GGA proteins.
The Journal of cell biology - 30 Oct 2000
Black M W, Pelham H R
Abstract excerpt
Pep12p is a yeast syntaxin located primarily in late endosomes. Using mutagenesis of a green fluorescent protein chimera we have identified a sorting signal FSDSPEF, which is required for transport of Pep12p from the exocytic pathway to late endosomes, from which it can, when overexpressed, reach the vacuole. When this signal is mutated, Pep12p instead passes to early endosomes, a step that is determined by its...
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