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Article

Cleavage of hepatitis C virus nonstructural protein 5A by a caspase-like protease(s) in mammalian cells.

Virology - 10 May 2000

Satoh S, Hirota M, Noguchi T, Hijikata M, Handa H, Shimotohno K

Abstract excerpt

Nonstructural 5A protein (NS5A) of hepatitis C virus (HCV) is localized in the cytoplasm although it has a functional nuclear localization signal. To clarify the determinant of NS5A cytoplasmic localization, various N- or C-terminal deleted NS5A mutants were generated and their subcellular localization was analyzed in cell lines after transient expression. N-terminal deleted forms of NS5A were localized in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10793006
DOI: 10.1006/viro.2000.0287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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