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Article

Characterization of a HCV NS5A protein derived from a patient with hepatoma.

Biochemical and biophysical research communications - 11 Feb 2005

Yeh Chau-Ting, Chang Mei-Huei, Shyu Wei-Chu, Chang Ming-Ling, Yang Po-Yi, Tsao Mei-Ling, Lai Hsin-Yu

Abstract excerpt

A cDNA encoding hepatitis C virus NS5A protein was isolated from the serum of a patient with hepatocellular carcinoma. The NS5A(HCC) was localized in both the cytoplasmic and nuclear fractions of Huh-7 cells. Immunoprecipitation and electrophoresis experiments showed four major phosphorylated species of NS5A(HCC), p58, p56, p53, and p50. Two mutants (NS5A(HCC-NLSmt) and NS5A(HCC-TSmt)) carrying mutations on the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15629144
DOI: 10.1016/j.bbrc.2004.11.165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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