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Article

Interaction of hepatitis C virus nonstructural protein 5A with core protein is critical for the production of infectious virus particles.

Journal of virology - 1 Aug 2008

Masaki Takahiro, Suzuki Ryosuke, Murakami Kyoko, Aizaki Hideki, Ishii Koji, Murayama Asako, Date Tomoko, Matsuura Yoshiharu, Miyamura Tatsuo, Wakita Takaji, Suzuki Tetsuro

Abstract excerpt

Nonstructural protein 5A (NS5A) of the hepatitis C virus (HCV) possesses multiple and diverse functions in RNA replication, interferon resistance, and viral pathogenesis. Recent studies suggest that NS5A is involved in the assembly and maturation of infectious viral particles; however, precisely how NS5A participates in virus production has not been fully elucidated. In the present study, we demonstrate that NS5A...

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Identifiers

PMID: 18524832
DOI: 10.1128/JVI.00826-08
PMCID: PMC2519576

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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