Nuclear localization of the NS3 protein of hepatitis C virus and factors affecting the localization.

doi:10.1128/JVI.71.7.4954-4961.1997

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Article

Nuclear localization of the NS3 protein of hepatitis C virus and factors affecting the localization.

Journal of virology - 1 Jul 1997

Muramatsu S, Ishido S, Fujita T, Itoh M, Hotta H

Abstract excerpt

Subcellular localization of the NS2 and NS3 proteins of hepatitis C virus was analyzed. In stable Ltk transfectants inducibly expressing an NS2-NS3 polyprotein (amino acids [aa] 810 to 1463), processed full-size NS2 (aa 810 to 1026) was detected exclusively in a cytoplasmic membrane fraction. On...

Topics

Animals
Cell Line
Cell Nucleus
Gene Expression Regulation, Viral
Genes, p53
HeLa Cells
Hepacivirus
Humans
Mice
Mutation
Subcellular Fractions
Transfection
Viral Nonstructural Proteins

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