Article
The C-A mismatch base pair and the single-strand terminus in the E. coli initiator tRNA(fMet) acceptor stem adopt unusual conformations.
FEBS letters - 28 Apr 2000
Zuleeg T, Vogtherr M, Schübel H, Limmer S
Abstract excerpt
Acceptor stem variants of tRNA(fMet) (Escherichia coli) have been characterized by nuclear magnetic resonance. The wild type contains a C1-A72 mismatch pair which is crucial for its biological function. For comparison, the mismatch was replaced by regular pairs U1-A72 and C1-G72. Further variants contain an altered discriminator base, G73, or a G1-C72/U73 combination. The stems of variants U1-A72/A73 and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
