Article
The Candida albicans CUG-decoding ser-tRNA has an atypical anticodon stem-loop structure.
Journal of molecular biology - 12 Nov 1999
Perreau V M, Keith G, Holmes W M, Przykorska A, Santos M A, Tuite M F
Abstract excerpt
In many Candida species, the leucine CUG codon is decoded by a tRNA with two unusual properties: it is a ser-tRNA and, uniquely, has guanosine at position 33 (G33). Using a combination of enzymatic (V1 RNase, RnI nuclease) and chemical (Pb(2+), imidazole) probing of the native Candida albicans ser-tRNACAG, we demonstrate that the overall tertiary structure of this tRNA resembles that of a ser-tRNA rather than a...
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