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Article

Association of genetic polymorphism of glutathione S-transferase M1, T1, P1 and susceptibility to bladder cancer.

European urology - 1 Aug 2005

Srivastava Daya Shankar Lal, Mishra Dhruva Kumar, Mandhani Anil, Mittal Balraj, Kumar Anant, Mittal Rama Devi

Abstract excerpt

OBJECTIVE: Glutathione-S-transferases (GSTs) are active in the detoxification of wide variety of endogenous or exogenous carcinogens. We examined the association of the GST gene polymorphism with sporadic bladder cancer patients in Northern India. MATERIAL AND METHODS: The study constituted of 106 bladder cancer cases and 370 age-matched controls. The GSTT1 and GSTM1 null genotypes were identified by multiplex...

Topics

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Carcinoma, Transitional Cell
Disease Susceptibility
Glutathione Transferase
India
Logistic Models

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Staging

Reverse Transcriptase Polymerase Chain Reaction

Urinary Bladder Neoplasms

Source

Identifiers

PMID: 16005379
DOI: 10.1016/j.eururo.2005.02.007

Genes

GSTM1
GSTT1
GSTP1

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