Article
Association between glutathione S-transferase M1 null variant and risk of bladder cancer in Chinese Han population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2014
Xu Wei, Wang Fa, Ying Li, Wang Hong-Hui
Abstract excerpt
Glutathione S-transferase M1 (GSTM1) is one of the most important families of phase II isoenzymes known to detoxify a variety of electrophilic compounds and carcinogens. The GSTM1 null variant is associated with decreased enzyme activity, and it has been assumed to be associated with bladder cancer. The association between the GSTM1 null variant and bladder cancer in the Chinese Han population was unclear owing...
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