Article
Phosphorylation and regulation of a Gq/11-coupled receptor by casein kinase 1alpha.
The Journal of biological chemistry - 30 Jun 2000
Budd D C, McDonald J E, Tobin A B
Abstract excerpt
Agonist-mediated receptor phosphorylation by one or more of the members of the G-protein receptor kinase (GRK) family is an established model for G-protein-coupled receptor (GPCR) phosphorylation resulting in receptor desensitization. Our recent studies have, however, suggested that an alternative route to GPCR phosphorylation may be an operation involving casein kinase 1alpha (CK1alpha). In the current study we...
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