Article
Herpes simplex virus 1 late gene expression is preferentially inhibited during infection of the TAF250 mutant ts13 cell line.
Virology - 25 Apr 2000
Dhar S, Weir J P
Abstract excerpt
A key component of the polymerase II transcription machinery is the transcription factor TFIID, a complex that contains the TATA-box binding protein and several (10-12) associated factors designated as TAFs (TBP-associated factors). ts13 cells, which contain a temperature-sensitive mutant in TAF250, the largest subunit of TFIID, exhibit promoter-specific defects in gene expression at the nonpermissive...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
