Article
Base excision repair and nucleotide excision repair contribute to the removal of N-methylpurines from active genes.
DNA repair - 6 Aug 2002
Plosky Brian, Samson Leona, Engelward Bevin P, Gold Barry, Schlaen Brenda, Millas Themistocles, Magnotti Michael, Schor Jonathan, Scicchitano David A
Abstract excerpt
Many different cellular pathways have evolved to protect the genome from the deleterious effects of DNA damage that result from exposure to chemical and physical agents. Among these is a process called transcription-coupled repair (TCR) that catalyzes the removal of DNA lesions from the transcribed strand of expressed genes, often resulting in a preferential bias of damage clearance from this strand relative to...
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