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Article

Smad1 and Smad5 have distinct roles during dorsoventral patterning of the zebrafish embryo.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Nov 1999

Dick A, Meier A, Hammerschmidt M

Abstract excerpt

Smad1 and smad5 encode transcription factors that have been implicated in the transduction of signaling by the bone morphogenetic proteins Bmp2 and/or Bmp4. Here we report the characterization of Smad1 and Smad5 from the zebrafish, Danio rerio. Although smad1, smad5, bmp2b, and bmp4 are all expressed during gastrulation and although all four proteins have ventralizing activities, they appear to play distinct...

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Identifiers

PMID: 10590480
DOI: 10.1002/(SICI)1097-0177(199911)216:3<285::AID-DVDY7>3.0.CO;2-L

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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