Article
Expression of arylamine N-acetyltransferase in human intestine.
Gut - 1 Mar 1998
Hickman D, Pope J, Patil S D, Fakis G, Smelt V, Stanley L A, Payton M, Unadkat J D, Sim E
Abstract excerpt
BACKGROUND: Arylamine N-acetyltransferases in humans (NAT1 and NAT2) catalyse the acetylation of arylamines including food derived heterocyclic arylamine carcinogens. Other substrates include the sulphonamide 5-aminosalicylic acid (5-ASA), which is an NAT1 specific substrate; N-acetylation of 5-A...
Topics
- Arylamine N-Acetyltransferase
- Cytosol
- Genotype
- Humans
- Immunohistochemistry
- Intestines
- Isoenzymes
- Polymorphism, Genetic