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Functional Characterization of the Candida albicans MNT1Mannosyltransferase Expressed Heterologously in Pichia pastoris

1 Jun 2000

Abstract excerpt

The alpha1,2-mannosyltransferase gene MNT1 of the human fungal pathogen Candida albicans has been shown to be important for its adherence to various human surfaces and for virulence (Buurman, E. T. , Westwater, C., Hube, B., Brown, A. P. J., Odds, F. C., and Gow, N. A. R. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 7670-7675). The CaMnt1p is a type II membrane protein, which is part of a family of proteins that...

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PMID: 10766761
DOI: 10.1074/jbc.m909699199

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