Article
Apolipoprotein E4: an allele associated with many diseases.
Annals of medicine - 1 Mar 2000
Smith J D
Abstract excerpt
Apolipoprotein E (apoE) was discovered as a plasma protein involved in lipoprotein metabolism. ApoE is synthesized by the liver and is also made locally in the brain. There are three common variants of apoE, resulting from common genetic variation, called E2, E3 and E4. The E3 allele is the most prevalent form, and the proportion of the three alleles differs between populations. Epidemiological studies have found...
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