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Article

Cancer risk estimation of genotoxic chemicals based on target dose and a multiplicative model.

Risk analysis : an official publication of the Society for Risk Analysis - 1 Apr 1999

Granath F N, Vaca C E, Ehrenberg L G, Törnqvist M A

Abstract excerpt

A mechanistic model and associated procedures are proposed for cancer risk assessment of genotoxic chemicals. As previously shown for ionizing radiation, a linear multiplicative model was found to be compatible with published experimental data for ethylene oxide, acrylamide, and butadiene. The validity of this model was anticipated in view of the multiplicative interaction of mutation with inherited and acquired...

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PMID: 10765407
DOI: 10.1023/a:1006933913194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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